Table 2.

In vitro T cell priming assay:

Group	IFN-γ(pg/ml)	IL-2 (pg/ml)
Wild-type DCs + T cells	48.0 ± 4.8	33.7 ± 5.7
TCRδ−/− DCs + T cells	43.3 ± 3.2	33.3 ± 5.8
CD4+ T cells + OVA	33.3 ± 8.4	33.3 ± 2.6
Wild-type DCs + OVA + CD4+ T cells	31,242 ± 1623	18,953 ± 759
TCRδ−/− DCs + OVA + CD4+ T cells	21,640 ± 835**	16,543 ± 392*

Purified naïve CD4⁺ T cells from OT II transgenic mice were co-cultured with DCs from WNV-infected wild-type or TCRδ^{−/ −} mice in the presence or absence of OVA 323–339. At 24 h post coculture, supernatant was harvested and measured for cytokine production using mouse Th1/Th2 cytokine kit. Data are presented as means ± SEM, n = 3.

^*P < 0.05 or

^**P < 0.01 for wild-type vs. TCRδ^{−/ −}.

P values were calculated with a non-paired Student’st test. Data shown were representative of two independent experiments.