TABLE 1.
Baseline demographic, clinical, and laboratory values in 742 maintenance hemodialysis patients at the start of the 5-y cohort study1
| All (n = 742) | Men (n = 391) | Women (n = 351) | P value2 | |
| Age (y) | 54 ± 153 | 53 ± 15 | 55 ± 15 | 0.13 |
| Race (% African American) | 31 | 28 | 34 | 0.06 |
| Ethnicity (% Hispanic) | 52 | 54 | 49 | 0.17 |
| Primary insurance (% receiving Medicare) | 52 | 51 | 52 | 0.74 |
| Diabetes mellitus (%) | 53 | 51 | 56 | 0.19 |
| Marital status (% married) | 48 | 60 | 37 | <0.01 |
| Charlson comorbidity score | 1.9 ± 1.6 | 1.9 ± 1.6 | 1.8 ± 1.6 | 0.95 |
| BMI (kg/m2) | 26.5 ± 5.8 | 25.3 ± 5.0 | 27.3 ± 6.4 | <0.01 |
| NIR interactance–measured body fat (%) | 26.4 ± 10.8 | 19.5 ± 18.1 | 34.1 ± 7.7 | <0.01 |
| NIR interactance–measured fat mass (kg) | 19.8 ± 11.5 | 15.3 ± 19.6 | 24.8 ± 11.4 | <0.01 |
| NIR interactance–measured LBM (kg) | 52.0 ± 10.9 | 58.6 ± 8.7 | 44.6 ± 8.0 | <0.01 |
| Triceps-skinfold thickness (mm) | 17.3 ± 9.5 | 12.9 ± 7.3 | 22.2 ± 9.9 | <0.01 |
| Biceps-skinfold thickness (mm) | 9.7 ± 7.8 | 7.3 ± 6.5 | 12.4 ± 8.2 | <0.01 |
| MAMC (cm) | 25.7 ± 4.3 | 26.3 ± 3.8 | 25.1 ± 4.8 | <0.01 |
| Dialysis vintage (mo) | 28 ± 26 | 27 ± 25 | 29 ± 26 | 0.95 |
| Dialysis dose, single pool (Kt/V) | 1.62 ± 0.30 | 1.53 ± 0.26 | 1.71 ± 0.31 | <0.01 |
| nPNA (kg/d) | 1.07 ± 0.22 | 1.09 ± 0.24 | 1.06 ± 0.22 | 0.10 |
| Serum albumin (mg/dL) | 3.90 ± 0.36 | 3.97 ± 0.37 | 3.82 ± 0.32 | <0.01 |
| Prealbumin (mg/dL) | 28.6 ± 9.5 | 29.6 ± 9.9 | 27.5 ± 9.0 | <0.01 |
| Creatinine (mg/dL) | 10.2 ± 3.2 | 10.9 ± 3.3 | 9.5 ± 2.9 | <0.01 |
| C-reactive protein (mg/L) | 5.6 ± 7.0 | 5.8 ± 7.7 | 5.4 ± 6.0 | <0.01 |
| IL-6 (pg/mL) | 11.7 ± 15.7 | 10.8 ± 12.2 | 11.8 ± 15.7 | <0.01 |
| TNF-α (pg/mL) | 8.6 ± 11.4 | 8.7 ± 12.4 | 8.5 ± 10.0 | <0.01 |
1
NIR, near-infrared; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α; LBM, lean body mass; MAMC, midarm muscle circumference; nPNA, total nitrogen appearance normalized to body weight; Kt/V, urea clearance over time.
2
Independent-samples t test for men compared with women.
3
Mean ± SD (all such values).