TABLE 10.
Death hazard ratios (and 95% CIs) of 5-y mortality according to fat mass (FM) quartiles in 351 female maintenance hemodialysis patients
| FM quartiles |
|||||
| 1 (n = 89) | 2 (n = 96) | 3 (n = 80) | 4 (n = 86) | P for trend1 | |
| Unadjusted | 1.00 | 0.71 (0.43, 1.17) | 0.84 (0.50, 1.40) | 0.96 (0.58, 1.57) | 0.96 |
| Adjusted for age and sex | 1.00 | 0.56 (0.33, 0.92)2 | 0.61 (0.36, 1.02) | 0.72 (0.43, 1.19) | 0.29 |
| Adjusted for case mix3 | 1.00 | 0.50 (0.29, 0.87)2 | 0.57 (0.32, 0.97)2 | 0.55 (0.31, 0.98)2 | 0.09 |
| Adjusted for case mix + inflammation4 | 1.00 | 0.45 (0.26, 0.78)2 | 0.45 (0.25, 0.80)2 | 0.38 (0.20, 0.71)2 | <0.01 |
1
Derived by using a Cox proportional hazards model.
2
P < 0.05.
3
Case-mix variables included age, sex, race-ethnicity, diabetes mellitus, dialysis vintage, insurance, marital status, modified Charlson comorbidity score, dialysis dose [Kt/V (urea clearance over time)], and residual urine.
4
Inflammatory markers: C-reactive protein, interleukin-6, and tumor necrosis factor-α.