TABLE 11.
Death hazard ratios (and 95% CIs) of 5-y mortality according to percentage fat mass (FM%) quartiles in 351 female maintenance hemodialysis patients
FM% quartiles |
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1 (n = 88) | 2 (n = 88) | 3 (n = 89) | 4 (n = 86) | P for trend1 | |
Unadjusted | 1.00 | 1.13 (0.68, 1.87) | 0.85 (0.50, 1.43) | 1.28 (0.78, 2.11) | 0.56 |
Adjusted for age and sex | 1.00 | 0.77 (0.45, 1.30) | 0.58 (0.34, 1.00)2 | 0.87 (0.52, 1.44) | 0.46 |
Adjusted for case mix3 | 1.00 | 0.78 (0.45, 1.33) | 0.61 (0.35, 1.07) | 0.85 (0.50, 1.44) | 0.43 |
Adjusted for case mix + inflammation4 | 1.00 | 0.59 (0.34, 1.04) | 0.53 (0.29, 0.95)2 | 0.57 (0.32, 1.03) | 0.07 |
Derived by using a Cox proportional hazards model.
P < 0.05.
Case-mix variables included age, sex, race-ethnicity, diabetes mellitus, dialysis vintage, insurance, marital status, modified Charlson comorbidity score, dialysis dose [Kt/V (urea clearance over time)], and residual urine.
Inflammatory markers: C-reactive protein, interleukin-6, and tumor necrosis factor-α.