TABLE 2.
Baseline demographic, clinical, and laboratory values in 391 male maintenance hemodialysis patients at the start of the 5-y cohort study, by lean body mass (LBM) quartile1
| LBM quartile |
|||||
| Variables | 1 (n = 100) | 2 (n = 97) | 3 (n = 98) | 4 (n = 96) | P for trend2 |
| Age (y) | 54 ± 153 | 53 ± 15 | 53 ± 16 | 51 ± 13 | 0.07 |
| Race (% African American) | 9 | 14 | 31 | 57 | <0.01 |
| Ethnicity (% Hispanic) | 67 | 68 | 53 | 28 | <0.01 |
| Primary insurance (% receiving Medicare) | 47 | 42 | 54 | 60 | 0.06 |
| Diabetes mellitus (%) | 54 | 53 | 44 | 52 | 0.47 |
| Marital status (% married) | 59 | 59 | 63 | 47 | 0.18 |
| Charlson comorbidity score | 2.0 ± 1.5 | 1.8 ± 1.8 | 1.6 ± 1.5 | 2.0 ± 1.7 | 0.70 |
| BMI (kg/m2) | 22.2 ± 3.1 | 23.6 ± 3.3 | 25.9 ± 4.1 | 29.7 ± 5.7 | <0.01 |
| Triceps-skinfold thickness (mm) | 10.7 ± 5.1 | 11.6 ± 5.5 | 12.3 ± 6.0 | 17.2 ± 10.6 | <0.01 |
| Biceps-skinfold thickness (mm) | 5.6 ± 3.8 | 6.1 ± 3.8 | 6.5 ± 4.0 | 10.8 ± 10.4 | <0.01 |
| MAMC (cm) | 23.7 ± 2.9 | 25.2 ± 3.0 | 26.7 ± 3.2 | 29.7 ± 3.1 | <0.01 |
| NIR interactance–measured body fat (%) | 17.1 ± 6.8 | 17.7 ± 6.3 | 19.6 ± 8.0 | 23.6 ± 9.4 | <0.01 |
| NIR interactance–measured fat mass (kg) | 10.4 ± 5.2 | 12.3 ± 5.3 | 15.7 ± 7.7 | 23.2 ± 12.8 | <0.01 |
| NIR interactance–measured LBM (kg) | 48.3 ± 3.4 | 55.1 ± 1.5 | 60.8 ± 1.9 | 70.6 ± 4.1 | <0.01 |
| Dialysis vintage (mo) | 25 ± 24 | 24 ± 23 | 24 ± 22 | 35 ± 28 | 0.01 |
| Dialysis dose, single pool (Kt/V) | 1.66 ± 0.28 | 1.55 ± 0.27 | 1.48 ± 0.20 | 1.44 ± 0.24 | <0.01 |
| nPNA (kg/d) | 1.13 ± 0.26 | 1.12 ± 0.23 | 1.08 ± 0.23 | 1.02 ± 0.23 | <0.01 |
| Serum albumin (mg/dL) | 3.96 ± 0.41 | 3.99 ± 0.38 | 4.00 ± 0.33 | 3.91 ± 0.32 | 0.20 |
| Prealbumin (mg/dL) | 28.9 ± 9.8 | 29.9 ± 10.9 | 29.7 ± 9.9 | 30.0 ± 9.0 | 0.65 |
| Creatinine (mg/dL) | 10.5 ± 3.2 | 10.5 ± 3.4 | 10.8 ± 3.2 | 11.9 ± 3.3 | <0.01 |
| C-reactive protein (mg/L) | 5.3 ± 5.5 | 5.2 ± 8.8 | 5.8 ± 6.1 | 6.7 ± 9.8 | 0.05 |
| IL-6 (pg/mL) | 11.4 ± 13.1 | 10.1 ± 9.9 | 9.2 ± 11.7 | 12.3 ± 13.5 | 0.49 |
| TNF-α (pg/mL) | 7.4 ± 5.9 | 8.7 ± 8.9 | 10.2 ± 17.2 | 8.7 ± 14.5 | 0.80 |
1
NIR, near-infrared; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α; MAMC, midarm muscle circumference; nPNA, total nitrogen appearance normalized to body weight; Kt/V, urea clearance over time.
2
P values for triceps- and biceps-skinfold thicknesses, dialysis dose (vintage), C-reactive protein, IL-6, and TNF-α are based on the logarithmic values of these measures (ANOVA).
3
Mean ± SD (all such values).