TABLE 6.
Death hazard ratios (and 95% CIs) of 5-y mortality according to lean body mass (LBM) quartiles in 391 male maintenance hemodialysis patients
LBM quartiles |
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Variables | 1 (n = 100) | 2 (n = 97) | 3 (n = 98) | 4 (n = 96) | P for trend1 |
Unadjusted | 1.00 | 0.76 (0.41, 1.40) | 1.44 (0.81, 2.55) | 1.28 (0.72, 2.26) | 0.14 |
Adjusted for age and sex | 1.00 | 0.81 (0.44, 1.52) | 1.54 (0.85, 2.79) | 1.58 (0.89, 2.91) | 0.05 |
Adjusted for case mix2 | 1.00 | 0.70 (0.37, 1.32) | 1.65 (0.90, 3.02) | 1.26 (0.66, 2.38) | 0.15 |
Adjusted for case mix + inflammation3 | 1.00 | 0.63 (0.32, 1.24) | 1.85 (0.94, 3.49) | 1.17 (0.60, 2.27) | 0.15 |
Derived by using a Cox proportional hazards model.
Case-mix variables included age, sex, race-ethnicity, diabetes mellitus, dialysis vintage, insurance, marital status, modified Charlson comorbidity score, dialysis dose [Kt/V (urea clearance over time)], and residual urine.
Inflammatory markers: C-reactive protein, interleukin-6, and tumor necrosis factor-α.