TABLE 7.
Death hazard ratios (and 95% CIs) of 5-y mortality according to fat mass (FM) quartiles in 391 male maintenance hemodialysis patients
| FM quartiles |
|||||
| 1 (n = 102) | 2 (n = 94) | 3 (n = 100) | 4 (n = 95) | P for trend1 | |
| Unadjusted | 1.00 | 0.87 (0.43, 1.61) | 1.38 (0.80, 2.40) | 1.15 (0.66, 2.02) | 0.35 |
| Adjusted for age and sex | 1.00 | 0.52 (0.28, 0.97)2 | 0.58 (0.32, 1.06) | 0.65 (0.36, 1.17) | 0.29 |
| Adjusted for case mix3 | 1.00 | 0.37 (0.19, 0.72)2 | 0.51 (0.28, 0.93)2 | 0.51 (0.28, 0.94)2 | 0.17 |
| Adjusted for case mix + inflammation4 | 1.00 | 0.33 (0.15, 0.69)2 | 0.50 (0.26, 0.97)2 | 0.51 (0.27, 0.96)2 | 0.22 |
1
Derived by using a Cox proportional hazards model.
2
P < 0.05.
3
Case-mix variables included age, sex, race-ethnicity, diabetes mellitus, dialysis vintage, insurance, marital status, modified Charlson comorbidity score, dialysis dose [Kt/V (urea clearance over time)], and residual urine.
4
Inflammatory markers: C-reactive protein, interleukin-6, and tumor necrosis factor-α.