TABLE 9.
Death hazard ratios (and 95% CIs) of 5-y mortality according to lean body mass (LBM) in 351 female maintenance hemodialysis patients
| LBM quartiles |
|||||
| Variables | 1 (n = 91) | 2 (n = 96) | 3 (n = 78) | 4 (n = 86) | P for trend1 |
| Unadjusted | 1.00 | 0.55 (0.33, 0.91)2 | 0.94 (0.58, 1.52) | 0.77 (0.47, 1.25) | 0.67 |
| Adjusted for age and sex | 1.00 | 0.51 (0.30, 0.85)2 | 0.85 (0.51, 1.42) | 0.69 (0.40, 1.21) | 0.44 |
| Adjusted for case mix3 | 1.00 | 0.47 (0.27, 0.79)2 | 0.70 (0.41, 1.20) | 0.49 (0.26, 0.90)2 | 0.07 |
| Adjusted for case mix + inflammation4 | 1.00 | 0.48 (0.28, 0.83)2 | 0.60 (0.34, 1.08) | 0.34 (0.17, 0.67)2 | <0.01 |
1
Derived by using a Cox proportional hazards model.
2
P < 0.05.
3
Case-mix variables included age, sex, race-ethnicity, diabetes mellitus, dialysis vintage, insurance, marital status, modified Charlson comorbidity score, dialysis dose [Kt/V (urea clearance over time)], and residual urine.
4
Inflammatory markers: C-reactive protein, interleukin-6, and tumor necrosis factor-α.