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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Biochemistry. 2010 Jun 1;49(21):4440–4449. doi: 10.1021/bi100394j

FIGURE 4.

FIGURE 4

The Q-loop region motif. The figure shows the deviant portion of the N-terminal NBD (left side) and the canonical counterpart from NBD2 (right side). A protein sequence logo depicting the conservation of residues in and around the Q-loops of NBDs 1 and 2 was constructed from the multiple sequence alignment of Pdr5p (Figure S1) as described previously (27). The height of each letter represents the probability of the residue occuring at that position in the alignment. The colors signify the chemistry of the amino acids: red, acidic; blue, basic; black, hydrophobic; green, polar.