TABLE 1.
Polycomb and trithorax group genes suppress piwi2?
| Stock | % suppresseda (n)b | Sourcec | Known domains/functionsd |
|---|---|---|---|
| cortotsT18 | 94 (17) | 4789 | Chromodomain protein |
| cortol1 | 81 (16) | 4788 | Chromodomain protein |
| Polycomb group genes | |||
| Pc1 | 0 (15) | 1728 | Chromodomain protein |
| P{w+mC =lacW}Mi-2j3D4 | 0 (28) | 12106 | ATP-dependent nucleosome mobilization |
| P{wph-p.418=418}e(Pc)84DET66.1 | 0 (12) | 4505 | Unknown |
| st1, in1, kniri-1, ScmD1 | 0 (11) | 2406 | Zinc-finger transcription factor |
| Trithorax group genes | |||
| ru1, h1, th1, st1, trxE2,ca1 | 4 (25) | 3621 | PHD domain (zinc-finger-like) protein |
| ash1B1 | 0 (19) | 5045 | Histone lysine N-methyltransferase activity (H3-K4 specific) |
| red1, e1, ash21 | 0 (12) | 4584 | PHD and FYVE/PHD domain (zinc-finger-like) protein |
| brm2 es ca1 | 0 (12) | 3619 | ATPase subunit of chromatin remodeling complex (yeast SWI/SNF) |
| kto1 ca1 | 0 (8) | 3618 | RNA polymerase II transcription mediator activity |
| ry506, P{ry+7.2 =PZ}mod(mdg4)03852 | 0 (12) | 11612 | BTB/POZ domain protein |
| mor1 | 0 (11) | 3615 | Myb DNA-binding domain and homeodomain-like protein |
| osa2 | 0 (10) | 3616 | ARID domain (DNA-binding domain) protein |
| P{ry+7.2 =PZ}Snr01319, ry506 | 0 (11) | 11529 | Brahma complex (Snf5-related) protein |
| P{w+mC =lacW}Trls2325 | 0 (11) | 12088 | GAGA factor |
a
The percentage of piwi2 If/piwi2 If; m/+ females containing >50% of suppressed ovarioles. m, mutation.
b
The total number of piwi2 If/piwi2 If; m/+ females examined.
c
The numbers refer to the Bloomington Drosophila Stock Center numbers.
d
The known domains/functions of the proteins based on FlyBase designations and published papers.