TABLE 4.
Multivariate Cox PH Models of Uniscale Scores
| Uniscale Sample Median Categorization | Uniscale CDS Categorization | |||
|---|---|---|---|---|
| Factors | p | HR (95% CI) | p | HR (95% CI) |
| Uniscale low vs. high scores | <0.0001 | 1.63 (1.29–2.06) | <0.0001 | 2.02 (1.46–2.79) |
| PS 1 and 2 vs. 0 | 0.10 | 1.22 (0.96–1.55) | 0.11 | 1.22 (0.96–1.55) |
| Age | 0.77 | 1.0 (0.99–1.01) | 0.55 | 1.0 (0.98–1.01) |
| Male vs. female | 0.26 | 1.19 (0.88–1.62) | 0.22 | 1.21 (0.89–1.64) |
| Anemia vs. non-anemia | 0.08 | 1.25 (0.97–1.60) | 0.14 | 1.21 (0.94–1.55) |
| ANC ≤ sample median vs. > sample median | 0.31 | 0.82 (0.57–1.19) | 0.24 | 0.80 (0.55–1.16) |
| PLT high vs. low levels | 0.20 | 1.20 (0.91–1.57) | 0.20 | 1.20 (0.91–1.57) |
| BMIa | ||||
| Underweight vs. normal | 0.03 | 1.87 (1.08–3.26) | 0.15 | 1.49 (0.86–2.58) |
| Overweight vs. normal | 0.27 | 0.86 (0.66–1.12) | 0.20 | 0.84 (0.65–1.09) |
| Obese vs. normal | 0.19 | 0.82 (0.61,1.10) | 0.13 | 0.79 (0.59–1.07) |
a
Likelihood ratio test for overall BMI effect: p = 0.004 for sample median categorization and p = 0.01 for CDS categorization. In the CDS categorization model, the significant differences were for overweight vs. underweight (p = 0.04, HR = 0.56), and obese vs. underweight (p = 0.03, HR = 0.53).
CDS, clinically deficient score (50); PS, performance score; ANC, absolute neutrophil count; PLT, platelet count; BMI, body mass index; HR, hazard ratio.