TABLE 4.

Influence of secondary objectives controlled for sex/gender, age, Thrombolysis in Myocardial Infarction (TIMI) risk score and patient preference

Controlled patient variable	Estimated risk of myocardial infarction*		Chest pain characterization†		Probability of significant CAD‡		Influence of patient opinion§
	Mean ± SE	P	Mean ± SE	P	Mean ± SE	P	Mean ± SE	P
Sex/gender		0.12		0.02		0.01		0.39
Male	2.47±0.06		2.66±0.04		4.67±0.07		2.90±0.14
Female	2.34±0.06		2.53±0.04		4.38±0.07		2.99±0.14
Age, years		0.26		<0.01		0.53		0.43
55	2.47±0.07		2.77±0.05		4.57±0.08		3.03±0.16
75	2.34±0.08		2.43±0.05		4.48±0.09		2.87±0.17
TIMI risk		<0.01		<0.01		<0.01		<0.01
Low	1.95±0.08		2.36±0.05		4.25±0.09		3.23±0.17
Moderate	2.36±0.08		2.48±0.05		4.43±0.09		2.97±0.17
High	2.90±0.06		2.95±0.05		4.89±0.08		2.64±0.15
Patient preference		0.43		0.10		<0.01		0.28
Agreeable for CC	2.47±0.08		2.58±0.07		4.71±0.09		2.69±0.21
Disagreeable for CC	2.39±0.09		2.69±0.07		4.29±0.1		3.12±0.21
No opinion	2.35±0.06		2.53±0.04		4.57±0.07		3.03±0.15

^*How would you characterize this patient’s level of risk of suffering a fatal or nonfatal myocardial infarction in the next 14 days? Score: 1 = low risk, 2 = moderate risk, 3 = high risk;

^†How would you characterize this patient’s chest pain? Score: 1 = noncardiac, 2 = possibly cardiac, 3 = definitely cardiac;

^‡Estimate the probability that this patient has significant coronary artery disease (CAD) (stenosis greater than 70%). Score: 1 = very unlikely to 5 = very likely;

^§How much does the patient’s opinion influence your decision to refer them for cardiac catheterization (CC)? Score: 1 = not very much to 5 = very much