TABLE 2.
Overall (n=1964) | Multiple risk factors (n=342) | Any 1 site (n=1370) | Any 2 or 3 sites (n=252) | Any CAD (n=1356) | Any CVD (n=390) | Any PAD (n=146) | |
---|---|---|---|---|---|---|---|
Cardiovascular events, % | |||||||
Cardiovascular death | 1.1 | 0.3 | 1.0 | 2.8 | 1.3 | 1.8 | 2.7 |
Cardiovascular death/MI/stroke | 2.6 | 2.0 | 2.1 | 6.3 | 2.7 | 4.6 | 4.8 |
Cardiovascular death/MI/stroke/cardiovascular hospitalization | 8.0 | 3.2 | 7.4 | 17.9 | 9.1 | 11.5 | 18.5 |
Hospitalizations involving no vascular interventions, event rates per 1000 patients | |||||||
Fatal MI | 2.5 | 0.0 | 1.5 | 11.9 | 3.7 | 5.1 | 6.8 |
Fatal stroke | 2.0 | 0.0 | 2.2 | 4.0 | 2.2 | 5.1 | 0.0 |
Other cardiovascular death | 6.6 | 2.9 | 6.6 | 11.9 | 6.6 | 7.7 | 20.5 |
Nonfatal stroke | 11.2 | 17.5 | 4.4 | 39.7 | 8.1 | 25.6 | 34.2 |
Nonfatal MI | 7.6 | 2.9 | 8.0 | 11.9 | 9.6 | 7.7 | 6.8 |
PAD – new diagnosis | 5.1 | 2.9 | 3.6 | 15.9 | 6.6 | 5.1 | 13.7 |
Worsening of claudication | 2.0 | 0.0 | 1.5 | 7.9 | 1.5 | 0.0 | 27.4 |
Unstable angina | 28.5 | 2.9 | 34.3 | 31.7 | 39.8 | 12.8 | 34.2 |
Transient ischemic attack | 7.1 | 2.9 | 6.6 | 15.9 | 6.6 | 15.4 | 13.7 |
Other ischemic event | 9.2 | 2.9 | 4.4 | 43.7 | 11.8 | 5.1 | 75.3 |
Chronic heart failure | 11.7 | 2.9 | 9.5 | 35.7 | 14.0 | 20.5 | 27.4 |
Bleeding with transfusion | 1.0 | 0.0 | 0.7 | 4.0 | 1.5 | 2.6 | 0.0 |
Hospitalizations involving vascular interventions, event rates per 1000 patients | |||||||
Coronary artery bypass grafting | 13.7 | 0.0 | 14.6 | 27.8 | 19.2 | 15.4 | 20.5 |
Percutaneous coronary intervention/stenting | 20.9 | 0.0 | 26.3 | 19.8 | 29.5 | 15.4 | 6.8 |
Carotid surgery | 4.6 | 5.8 | 2.9 | 11.9 | 2.9 | 10.3 | 13.7 |
Carotid angioplasty/stenting | 0.5 | 0.0 | 0.7 | 0.0 | 0.0 | 2.6 | 0.0 |
Lower limb amputation | 5.1 | 0.0 | 4.4 | 15.9 | 4.4 | 5.1 | 41.1 |
Peripheral angioplasty/stenting | 3.1 | 2.9 | 2.9 | 4.0 | 1.5 | 2.6 | 27.4 |
Peripheral bypass graft | 9.2 | 0.0 | 8.8 | 23.8 | 10.3 | 10.3 | 61.6 |
CAD Coronary artery disease; CVD Cerebrovascular disease; MI Myocardial infarction; PAD Peripheral arterial disease