Skip to main content
. Author manuscript; available in PMC: 2011 Sep 24.
Published in final edited form as: Biochem Biophys Res Commun. 2010 Aug 26;400(3):413–418. doi: 10.1016/j.bbrc.2010.08.092

Figure 2. WW domain of BAG3 is critical for cell motility and adhesion.

Figure 2

(A) Cells transfected with BAG3ΔWW deletion have impaired integrin-mediated adhesion. Cos7 cells were transfected by BAG3 wild type (BAG3), WW domain deleted (ΔWW) and pEGFP empty vector, followed by adhesion assay (*p<0.01, mean ± SD, n=6). (B) Impaired cell motility found in Cos7 cells with BAG3ΔWW (*p<0.01, mean ± SD, n=6). (C) BAG3 wild type (pEGFP-BAG3) and pEGFP-BAG3ΔWW were transfected into 293T cells. Western blotting with GFP antibody indicated stable expression.