. Author manuscript; available in PMC: 2010 Oct 14.

Published in final edited form as: IEEE Symp Comput Intell Data Min. 2007 Mar 1;2007:624–629. doi: 10.1109/CIDM.2007.368934

TABLE 1.

Apriori Results

Each evaluation was performed on 100 datasets of each genetic model (THB, THG, THL, and THO), keeping the best rule only or the top 5 rules in the ruleset. For each set of 100 datasets, the frequency of observing 0, 1, 2, 3, and 4 functional variables per ruleset was recorded. The frequency of detecting each individual locus A, B, C, and D is also listed as power by variables. FPR is the false positive rate, defined as the proportion of non-functional variables to total variables. Blank cells indicate a frequency is not applicable, for example the THO model contains only two functional variables A and B, so no more than 2 functional variables will ever be observed, and variables C and D are not included. Evaluations A and B use confidence as a rule metric. All others use IDP. Support and confidence cutoffs are denoted with S and C, and the use of bootstrapping is also noted.

A
			# Functional Variables					Power by Variables
			0	1	2	3	4	A	B	C	D	FPR
S10 C80	Best Rule	THB	68	0	32	0	0	0	0	32	32	0.11
		THG	5	0	94	1		95	95	1		0.01
		THL	95	3	2	0		2	1	4		0.16
		THO	0	0	100			100	100			0.01
	Top 5	THB	68	0	32	0	0	0	0	32	32	0.12
		THG	4	0	95	1		96	96	1		0.08
		THL	96	2	2	0		2	1	3		0.15
		THO	0	0	100			100	100			0.23

B
			# Functional Variables					Power by Variables
			0	1	2	3	4	A	B	C	D	FPR
S10 C50	Best Rule	THB	31	3	66	0	0	0	1	66	68	0.32
		THG	32	68	0	0		0	0	68		0.32
		THL	3	97	0	0		18	14	65		0.04
		THO	0	100	0			50	50			0.01
	Top 5	THB	2	2	86	10	0	4	7	69	97	0.72
		THG	22	72	6	0		8	3	73		0.81
		THL	1	22	48	29		61	61	83		0.50
		THO	0	4	96			99	97			0.45

C
			# Functional Variables					Power by Variables
			0	1	2	3	4	A	B	C	D	FPR
IDP S5 C5	Best Rule	THB	0	1	99	0	0	1	2	98	98	0.00
		THG	0	0	99	1		100	100	1		0.00
		THL	1	47	52	0		52	50	49		0.01
		THO	0	5	95			98	97			0.00
	Top 5	THB	0	0	90	4	6	11	9	98	98	0.01
		THG	0	0	94	6		100	100	6		0.00
		THL	1	6	42	51		81	84	78		0.23
		THO	0	0	100			100	100			0.05

D
			# Functional Variables					Power by Variables
			0	1	2	3	4	A	B	C	D	FPR
B-strap IDP S5 C5	Best Rule	THB	0	1	98	1	0	3	3	97	97	0.01
		THG	0	0	99	1		100	100	1		0.01
		THL	0	60	39	1		39	47	55		0.02
		THO	0	4	96			98	98			0.01
	Top 5	THB	0	0	83	5	12	15	16	99	99	0.02
		THG	0	0	86	14		100	100	14		0.00
		THL	0	4	38	58		84	89	81		0.22
		THO	0	0	100			100	100			0.02

E
			# Functional Variables					Power by Variables
			0	1	2	3	4	A	B	C	D	FPR
IDP S10 C5	Best Rule	THB	1	1	98	0	0	1	2	97	97	0.00
		THG	0	0	100	0		100	100	0		0.00
		THL	2	47	51	0		51	49	49		0.01
		THO	0	6	94			97	97			0.01
	Top 5	THB	0	0	90	4	6	11	9	98	93	0.01
		THG	0	0	93	7		100	100	7		0.00
		THL	2	7	42	49		79	82	77		0.24
		THO	0	0	100			100	100			0.10

F
			# Functional Variables					Power by Variables
			0	1	2	3	4	A	B	C	D	FPR
B-strap IDP S10 C5	Best Rule	THB	1	1	98	0	0	2	3	96	96	0.00
		THG	0	1	99	0		99	99	1		0.00
		THL	0	60	40	0		39	46	55		0.02
		THO	0	0	100			100	100			0.02
	Top 5	THB	0	0	83	5	12	15	16	99	99	0.02
		THG	0	0	85	15		100	100	15		0.00
		THL	0	4	38	58	0	84	88	82		0.23
		THO	0	0	100			100	100			0.04

G
			# Functional Variables					Power by Variables
			0	1	2	3	4	A	B	C	D	FPR
IDP S20 C5	Best Rule	THB	6	2	92	0	0	3	3	90	90	0.00
		THG	0	1	99	0		99	99	1		0.00
		THL	9	73	17	1		25	28	57		0.05
		THO	0	100	0			53	47			0.01
	Top 5	THB	5	1	79	8	7	16	11	92	92	0.02
		THG	0	0	39	61		100	100	61		0.08
		THL	9	40	29	22		45	45	74		0.35
		THO	0	0	100			100	100			0.05

H
			# Functional Variables					Power by Variables
			0	1	2	3	4	A	B	C	D	FPR
B-strap IDP S20 C5	Best Rule	THB	1	6	93	0	0	7	9	88	88	0.01
		THG	0	11	89	0		89	89	11		0.01
		THL	0	95	4	1		19	24	63		0.03
		THO	0	100	0			56	44			0.01
	Top 5	THB	0	2	29	46	23	45	49	98	98	0.24
		THG	0	0	20	80		100	100	80		0.09
		THL	0	20	56	24		65	57	82		0.41
		THO	0	11	89			97	92			0.26

I
			# Functional Variables					Power by Variables
			0	1	2	3	4	A	B	C	D	FPR
IDP S30 C5	Best Rule	THB	93	7	0	0	0	4	3	0	0	0.00
		THG	44	56	0	0		0	0	56		0.00
		THL	13	87	0			12	15	60		0.00
		THO	0	100	0			54	46			0.00
	Top 5	THB	93	7	0	0	0	4	3	0	0	0.00
		THG	43	57	0	0		0	0	57		0.01
		THL	13	55	32			26	22	71		0.02
		THO	0	2	98			100	98			0.05

J
			# Functional Variables					Power by Variables
			0	1	2	3	4	A	B	C	D	FPR
B-strap IDP S30 C5	Best Rule	THB	24	52	24	0	0	22	30	24	24	0.24
		THG	6	79	15	0		15	15	79		0.05
		THL	0	100	0	0		17	20	63		0.01
		THO	0	99	1			97	92			0.26
	Top 5	THB	16	33	25	24	2	38	48	39	38	0.52
		THG	3	57	9	31		37	37	94		0.49
		THL	0	9	69	22		58	62	93		0.20
		THO	0	1	99			100	99			0.03