TABLE 4.

Renal function after conversion from CsA to FK506^a

	Time after FK506 conversion (weeks)
	0	1	4	12	26	52
No. patients	48	48	48	43	32	20
Mean SCR (mg/dl ± SD)	3.20 ± 1.6	3.20 ± 1.9	2.57 ± 1.1	2.39 ± 0.9	2.20 ± 0.8	2.25 ± 0.9
Range	1.0–7.2	0.5–9.8	0.4–6.5	0.7–5.7	0.7–4.3	1.1–4.7
P (vs. time 0)	NAb	0.90	0.003	0.003	0.004	0.002
Mean BUN (mg/dl ± SD)	52.2±31.0	55.4 ± 33.5	42.0 ± 20.8	40.4 ± 18.6	35.8 ± 13.2	35.3 ± 14.8
Range	12–154	14–149	11–116	19–91	16–58	16–57
P (vs. time 0)	NA	0.1	0.05	0.03	0.01	0.03

^aExcluding patients on dialysis at the time of conversion to FK506.

^bNA: not applicable.