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. Author manuscript; available in PMC: 2011 Feb 26.
Published in final edited form as: Mol Cell. 2010 Feb 26;37(4):469–480. doi: 10.1016/j.molcel.2010.01.020

Figure 4.

Figure 4

The gcn5Δ and H3 5KR mutants affect cell cycle progression and cell cycle dynamics of H3K56Ac. (A-B) The gcn5Δ cells exhibit a prolonged G2/M phase and persistence of high levels of H3K56Ac compared to wild-type cells. Every 15 minutes after release from G1, aliquots of cells were removed for analysis of DNA content (A) or analysis of H3K56Ac and H3K27Ac by Western blot (B). (C-D) Cells expressing the H3 5KR mutant showed a prolonged G2/M phase and persistence of a high level of H3K56Ac compared to wild-type cells. The experiments were performed as described in A and B.