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. 2010 Sep 15;151(11):5185–5194. doi: 10.1210/en.2010-0519

Figure 3.

Figure 3

Physiological analysis of β-M3-Q490L Tg mice and control littermates maintained on regular mouse chow. A, Growth curves of male mice maintained on regular mouse chow (n = 10 per group). B, Fed blood glucose levels (WT, n = 8; β-M3-Q490L Tg, n = 10; male mice). C, IGTT. Blood glucose levels were measured at the indicated time points after ip administration of glucose (2 mg/g body weight; 16-wk-old males; n = 6 per group). D, Serum insulin levels after ip administration of glucose (2 mg/g body weight; 16-wk-old males; n = 6 per group). E, OGTT. Blood glucose levels were measured at the indicated time points after oral administration of glucose (2 mg/g body weight; 16-wk-old males; n = 6 per group). F, Serum insulin levels after oral administration of glucose (2 mg/g body weight; 16-wk-old males; n = 6 per group). G, Insulin tolerance test (ITT). Blood glucose levels were measured at the indicated time points after ip administration of insulin (0.75 U/kg; 20-wk-old males; n = 6 per group). Data are expressed as means ± se. *, P < 0.05; **, P < 0.01, compared with the corresponding WT value.