Table 2.
WT | β-M3-Q490L Tg | |
---|---|---|
Regular chow | ||
Blood glucose (mg/dl) | ||
Fed | 149.9 ± 5.8 | 89.3 ± 5.6b |
Fasted | 122.6 ± 9.0 | 61.5 ± 2.9b |
Serum insulin (ng/ml) | ||
Fed | 12.2 ± 1.0 | 26.0 ± 0.7b |
Fasted | 0.94 ± 0.10 | 3.0 ± 0.9a |
High-fat diet | ||
Blood glucose (mg/dl) | ||
Fed | 205.0 ± 5.7 | 155.1 ± 17.1b |
Fasted | 179.8 ± 9.4 | 83.3 ± 5.1b |
Serum insulin (ng/ml) | ||
Fed | 22.8 ± 2.7 | 31.0 ± 0.6a |
Fasted | 3.5 ± 0.4 | 18.3 ± 1.0b |
Measurements were carried out with 16- to 24-wk-old male mice (n = 6–10 per genotype). Data are given as means ± se. P values are as compared with the corresponding WT control group.
P < 0.05.
P < 0.01.