Table 2.
Main clinical features and treatment outcome of sAPL patients
| Patient no. | Age (y) at time of APL diagnosis | Sex | APL characteristics |
Therapy of APL | Outcome | ||
|---|---|---|---|---|---|---|---|
| WBC, ×109/L | PLT, ×109/L | DIC, Yes/No | |||||
| UPN 1 | 60 | F | 5.5 | 25 | Yes | PETHEMA APL 2005 | Died at 7 months due to cerebral hemorrhage |
| UPN 2 | 59 | F | 8.9 | 74 | Yes | GIMEMA AIDA protocol | CCR 21 mo |
| UPN 3 | 58 | F | 0.5 | 37 | No | PETHEMA APL 2005 | CCR 16 mo |
| UPN 4 | 36 | F | 0.8 | 74 | No | GIMEMA AIDA protocol | CCR 16 mo |
| UPN 5 | 26 | F | 1.1 | 30 | Yes | GIMEMA AIDA protocol | CCR 24 mo |
| UPN 6 | 59 | F | 1.1 | 58 | Yes | GIMEMA AIDA protocol | CCR 19 mo |
| UPN 7 | 28 | M | 0.7 | 5 | No | UK MRC protocol | Relapse at 28 mo |
| UPN 8 | 61 | M | 3.3 | 31 | No | PETHEMA APL 2005 | CCR 4 mo |
| UPN 9 | 45 | M | 13 | 12 | No | GIMEMA AIDA protocol | CCR 4 mo |
| UPN 10 | 27 | M | 33.7 | 11 | Yes | GIMEMA AIDA protocol | CCR 10 mo |
| UPN 11 | 45 | M | 0.6 | 66 | No | GIMEMA AIDA protocol | CCR 10 mo |
| UPN 12 | 67 | M | 1.1 | 9 | No | PETHEMA APL 2005 | CCR 9 mo |
| UPN 13 | 55 | F | 8.9 | 13 | Yes | NA | Died 3 h after APL diagnosis |
| UPN 14 | 45 | F | 72.2 | 40 | Yes | PETHEMA APL 2005 | CCR 1 mo |
DIC indicates disseminated intravascular coagulation; CCR, continuous complete remission; and NA, not applicable.