Table 5.
Multivariate analyses of survival, leukemia-free survival, treatment-related mortality, and relapse in patients undergoing transplantation for advanced phase chronic myeloid leukemia
Variable | n | Relative risk of death (95% CI) | P |
---|---|---|---|
Survival | |||
Main effect | |||
No imatinib | 216 | 1.00* | |
Imatinib | 216 | 0.93 (0.74-1.18) | .570† |
Leukemia-free survival | |||
Main effect | |||
No imatinib | 216 | 1.00* | |
Imatinib | 216 | 1.05 (0.84-1.32) | .670† |
Treatment-related mortality | |||
Main effect | |||
No imatinib | 216 | 1.00* | |
Imatinib | 216 | 0.87 (0.64-1.18) | .350† |
Other significant covariates | |||
Karnofsky score at transplantation | .007‡ | ||
> 80% | 276 | 1.00* | |
≤ 80% | 122 | 1.67 (1.21-2.31) | .002 |
Unknown | 34 | 1.08 (0.60-1.94) | .790 |
Relapse | |||
Main effect | |||
No imatinib | 216 | 1.00* | |
Imatinib | 216 | 1.35 (0.95-1.89) | .090† |
Reference group.
One degree of freedom.
Two degrees of freedom.