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. 2010 Oct 14;5(10):e13402. doi: 10.1371/journal.pone.0013402

Figure 2. Repeating sequence elements in Pur-α.

Figure 2

(A) Schematic drawing of human Pur-α. Numbers above the schemes indicate amino acid positions with respect to the start codon. A previous study described three class I and two class II sequence repeats in the central nucleic-acid binding region of human Pur-α [12], [13], [16]. (B) Using HHrepID, we instead identified three so-called PUR repeats, which overlap only partially with the previously assigned repeats. (C) Amino acid sequence alignment of the PUR repeats in human (h), D. melanogaster (Dm), and B. burgdorferi (Bb) Pur-α. Zappo color code as follows: pink: aliphatic/hydrophobic, orange: aromatic, blue: positive, red: negative, green: hydrophilic, yellow: cysteine. (D) Amino acid-sequence identity/similarity of PUR repeats in Pur-α from D. melanogaster (Dm), human (h), and B. burgdorferi (Bb).