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. 2010 Oct 14;6(10):e1001154. doi: 10.1371/journal.pgen.1001154

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Huang et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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This plot shows the fold of enrichment of predicted HI genes in dominant genes relative to recessive genes (thick solid line) as a function of the proportion of top predictions labeled as being haploinsufficient. Also plotted is the transformed p value (−log₁₀(p)) of the corresponding Fisher's exact test (thick dashed line). The horizontal dashed line marks the p value of 0.05.