Table 1. Neutrality tests.

Population	All SNPs				Coding SNPs				Coding
	S	TajD	p(TajD)	p(MWU)	S	TajD	p(TajD)	p(MWU)	p(HKA)
ERAP2
Yoruba	45	2.05	0	0	10	1.43	0.004	0.017	0.525
Luhya	51	1.44	0.000	0.000	11	0.95	0.026	0.145	0.400
Palestinian	55	1.34	0.004	0.001	13	1.05	0.094	0.028	0.019
Gujarati	45	1.99	0	0	12	1.05	0.105	0.068	0.033
Han	38	2.68	0	0	9	1.95	0.008	0.001	0.150
Toscani	40	2.30	0	0	11	1.17	0.078	0.085	0.067
ERAP1
Yoruba	52	0.19	0.032	0.048	20	0.10	0.185	0.242	0.016
Luhya	55	−0.06	0.113	0.139	19	0.16	0.158	0.201	0.023
Palestinian	58	0.38	0.196	0.038	22	0.08	0.435	0.311	0
Gujarati	54	0.44	0.173	0.082	22	0.18	0.382	0.327	0.000
Han	41	0.91	0.027	0.010	18	0.55	0.202	0.131	0.000
Toscani	49	1.07	0.012	0.007	17	1.16	0.057	0.037	0.002

The number of SNPs (S) and results for the three neutrality tests performed for ERAP2 and ERAP1 using data generated from the six populations are indicated [TajD: Tajima's D; p(TajD): P-value for Tajima's D test; p(MWU): P-value for MWUhigh test; p(HKA): P-value for HKA test]. HKA was performed only for the coding regions of the genes. The complete matrix with summary statistics is presented in Table S1.