Table 1.
Distribution of EGFR gene copy number evaluated by CISH according to tumor histotype
| Histotype | N° of cases | Disomy | Trisomy | Polysomy | Amplified |
|---|---|---|---|---|---|
| ADC | 7 | 1 | 2 | 3 | 1 |
| LCC | 8 | 2 | 1 | 4 | 1 |
| SCC | 5 | 1 | 3 | 1 | 0 |
| mCRC | 13 | 2 | 4 | 7 | 0 |
| Total | 33 | 6 | 10 | 15 | 2 |
ADC: adenocarcinoma; LCC: large cell carcinoma; SCC: squamous cell carcinoma; mCRC: metastatic colo-rectal cancer; Disomy: 1.6-2.0 balanced gene and chromosome 7; Trisomy: balanced 2.2-3.0 gene and chromosome 7; Polysomy: 3.1-4.4 balanced gene and chromosome 7; Amplified: gene-to-chromosome 7 ratio ≥ 2