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Primary outcome measures in donepezil and placebo patients. A, V-ADAS-cog least-squares (LS) mean change from baseline; B, CIBIC-Plus overall change at end point. C, V-ADAS-cog LS mean change from baseline for patients with Scheltens’ score <2. D, V-ADAS-cog LS mean change from baseline for patients with Scheltens’ score ≥2. CMH indicates Cochran-Mantel-Haenszel; LOCF, last observation carried forward.
