Table 2.

Performance characteristics of SIAscopy for the diagnosis of 'suspicious' in the different datasets of lesions.

	Development dataset (Moncrieff scoring system)	UK validation dataset (PCSA)	Australian validation dataset (PCSA)
Sensitivity (95% CI)	0.54 (0.35 - 0.72)	0.50 (0.18-0.81)	0.44 (0.32-0.58)
Specificity (95% CI)	0.77 (0.73 - 0.81)	0.84 (0.78-0.88)	0.95 (0.93-0.97)
Positive predictive value (95% CI)	0.12 (0.075 - 0.20)	0.09 (0.03-0.22)	0.52 (0.38-0.66)
Negative predictive value (95% CI)	0.96 (0.93 - 0.98)	0.98 (0.95-0.99)	0.95 (0.92-0.96)