Table 3.
Comparison of the parameters of HDL oxidation between HDL particles derived from the low-HDL-C and control subjects
| Low-HDL-C | Control | P value | ||
|---|---|---|---|---|
| Lag time (minute) | ||||
| Total HDL oxidation | 66.47 | 69.19 | 0.326 | |
| (56.35 - 96.54) | (56.16 - 78.50) | |||
| HDL3 oxidation | 69.40 | 64.04 | 0.206 | |
| (55.75 - 96.51) | (54.44 - 82.45) | |||
| P value | 0.427 | 0.176 | ||
| Propagation rate (nmol/mgHDL or HDL3/min) | ||||
| Total HDL oxidation | 1.242 | 1.543 | < 0.0001 | |
| (1.097 - 1.362) | (1.431 - 1.795) | |||
| HDL3 oxidation | 1.032 | 1.022 | 0.533 | |
| (0.924 - 1.123) | (0.807 - 1.159) | |||
| P value | < 0.0001 | < 0.0001 | ||
| Maximal dienes (nmol/mgHDL or HDL3) | ||||
| Total HDL oxidation | 86.67 | 107.47 | 0.002 | |
| (76.38 - 103.31) | (97.62 - 114.87) | |||
| HDL3 oxidation | 71.47 | 71.57 | 0.646 | |
| (63.26 - 78.45) | (60.89 - 84.22) | |||
| P value | < 0.0001 | < 0.0001 | ||
Data are expressed as median (lower and upper quartile). Statistical significances were adjusted for age, sex, and smoking status between low HDL and control subjects.