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Transmission electron microscopy of CyPrP aggregates. N2a cells were transiently transfected with CyPrP and processed for electron microscopy. (a, b) Electron-dense particles in CyPrP-expressing cells at 16 h (a) and 24 h (b) after transfection. (c) Higher magnification of section indicated by white box in (b) showing mitochondria clustering around an aggresome. (d) Mock-transfected cells. n, nucleus; m, mitochondria. Scale bar 500 nm.
