Skip to main content
. Author manuscript; available in PMC: 2010 Oct 14.
Published in final edited form as: Arch Immunol Ther Exp (Warsz). 2008 May 30;56(3):165–180. doi: 10.1007/s00005-008-0023-4

Fig. 3.

Fig. 3

Stem cell markers expressed in both embryonal carcinomas and seminomas. Pluripotency regulators POU5F1/Oct 3/4 and NANOG are expressed both in embryonal carcinomas and seminomas as shown here by immunohistochemical staining on a seminoma sample (A –POU5F1, B – NANOG). In contrast, pluripotency regulator SOX2 is differentially expressed in embryonal carcinoma only (C – embryonal carcinoma component of a TGCT with a mixed histology expressing SOX2, D – compare a completely negative staining in a seminoma). Bar=100 μm.