Table 4.
Clinical characteristics of 9 patients positive for anti-p140 antibody
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | |
|---|---|---|---|---|---|---|---|---|---|
| Age at myositis diagnosis | 48 | 67 | 18 | 46 | 55 | 21 | 53 | 51 | 53 |
| Sex | F | F | M | M | F | F | F | M | M |
| Diagnosis | DM | DM | DM | DM | DM | DM | DM | DM | DM |
| Interstitial lung disease | + | + | - | + | + | - | - | + | + |
| Rapidly progressive type | No | Yes | No | Yes | Yes | Yes | |||
| Muscle weakness | + | + | + | + | + | + | + | + | + |
| Creatine kinase† | 31 | 20 | 486 | 212 | 930 | 19487 | 775 | 1273 | 140 |
| Lactate dehydrogenase† | 280 | 407 | 765 | 493 | 437 | 6916 | 748 | 295 | 249 |
| Abnormal electromyography | + | + | + | + | + | + | + | + | + |
| Biopsy proven myositis | + | + | + | + | + | + | + | + | + |
† Normal range; 20-270 IU/mL for creatine kinase and 100-225 IU/mL for lactate dehydrogenase
DM = dermatomyositis, F = female, M = male