Table 1.
Urodynamic Study and Bladder Volume of Experimental and Control Groups at 28 and 56 Days after Transplantation.
| PTD28 | PTD56 | p-value | |||||
|---|---|---|---|---|---|---|---|
| PBS (n = 7) | hFb (n = 11) | hMSC (n = 9) | PBS (n = 7) | hFb (n = 9) | hMSC (n = 6) | ||
| Voiding frequency (time/min) | 0.80 ± 0.09 | 0.82 ± 0.16 | 0.76 ± 0.32 | 0.79 ± 0.11 | 0.82 ± 0.19 | 0.92 ± 0.07 | >0.05* |
| Maximal pressure (cmH2O) | 9.21 ± 5.30 | 9.60 ± 4.2 | 9.70 ± 4.11 | 9.00 ± 5.77 | 8.11 ± 7.39 | 10.33 ± 4.50 | >0.05* |
| Pattern of regularity (%)† | 43 | 45 | 44 | 43 | 22 | 50 | >0.05* |
| Detrusor contraction without voiding (%)† | 43 | 36 | 44 | 43 | 44 | 50 | >0.05* |
| Gross pattern of voiding (%)† | >0.05* | ||||||
| Flaccid | 29 | 27 | 13 | 29 | 33 | 17 | |
| Hyperreflexia | 71 | 73 | 87 | 71 | 67 | 83 | |
| Normal | 0 | 0 | 0 | 0 | 0 | 0 | |
| Bladder volume (mm*) | 1345.25 ± 1206.27 | 1263.75 ± 838.05 | 1279.57 ± 1310.69 | 1874.47 ± 1452.13 | 1925.99 ± 1591.44 | 1594.45 ± 703.36 | >0.05* |
PTD: post-transplantation day, PBS: control group received phosphate-buffered saline, hFb: control group received human fibroblast, hMSC: experimental group received human mesenchymal stem cell * by one-way AVOVA, ** by Fisher's exact test, † No. of detectable cases (%)