Table 4. Comparison of manually examined hinge loops and hinge loops identified by the proposed method.

Closed form	Open form	Hinge loops examined by [2]		Hinge loops identified by the proposed method		Length difference of hinge loops1 (residues)	Shift of the centers of hinge loops2 (residues)
		Rangee *	Lengthe	Rangei	Lengthi
1msbA	1ixxA	72-75	4	72-80	9	−5	2.5
2ezmA	3ezmA	50-53	4	49-54	6	−2	0
1hz5A	1jmlA	52-55	4	52-56	5	−1	0.5
1wwwX	1wwbX	299-301	3	297-300	4	−1	1.5
1orcA	5croA	55-55	1	55-56	2	−1	0.5
1orcA	5croA	55-56	2	55-56	2	0	0
1sncA	1sndA	112-120	9	112-120	9	0	0
1mupA	1obpA	126-130	5	126-130	5	0	0
1fynA	1aojA	112-118	7	112-118	7	0	0
1sncA	1sndA	112-120	9	112-120	9	0	0
1mupA	1obpA	121-124	4	121-124	4	0	0
1fynA	1aojA	34-49	16	34-49	16	0	0
1brnL	1yvsA	37-41	5	37-41	5	0	0
5rsaA	1bsrA	15-22	8	15-22	8	0	0
1wwwX	1wwaX	297-299	3	296-298	3	0	1
1dksA	1cksA	60-65	6	60-65	6	0	0
1msbA	1ixxA	93-98	6	95-100	6	0	2
1griA	1fyrA	121-123	3	121-123	3	0	0
1nloC	1aojA	34-39	6	34-39	6	0	0
1mdtA	1ddtA	379-387	9	379-386	8	1	0.5
1qmpA	1dz3A	103-109	7	106-111	6	1	2.5
1wwwX	1wwcA	317-319	3	316-317	2	1	1.5
1k3sA	1k3eA	33-36	4	34-36	3	1	0.5
1eydA	1sndA	112-120	9	113-120	8	1	0.5
1pv3A	1k04A	943-948	6	943-947	5	1	0.5
1qd0A	1sjvA	95-100	6	94-98	5	1	1.5
1cunA	2spcA	72-75	4	72-73	2	2	1
1gmfA	1hulA	87-99	13	87-97	11	2	1
1qlxA	1i4mA	188-198	11	189-197	9	2	0
5rsaA	1f0vA	112-115	4	112-113	2	2	1
5rsaA	1js0A	112-115	4	112-113	2	2	1
1cewI	1g96A	55-59	5	57-59	3	2	1
5rsaA	1a2wA	15-22	8	18-22	5	3	1.5
1a5pA	1a2wA	15-22	8	18-22	5	3	1.5
1gmfA	1hulA	82-89	8	82-85	4	4	2
1hngA	1cdcA	44-50	7	44-46	3	4	2
4icbA	1ht9A	38-47	10	41-45	5	5	0.5
4gcrA	1blbA	79-87	9	86-87	2	7	3.5
				Unsigned average		1.4	0.8

^*According to [2], this range was determined for the protein indicated by the bold italic text.

¹The length difference of the hinge loops was calculated as Length_e – Length_i.

²This shift was calculated as the distance between the center of Range_e and the center of Range_i.