Figure 1.

Examples of evoked calcium responses to either 50 mM KCl or 10 mM denatonium benzoate in isolated taste receptor cells. (A) A 10-s application of 50 mM KCl (arrow) caused a large increase over baseline values in taste cells that express VGCCs. After an initial rapid clearance of calcium, a plateau phase was present that eventually returned to baseline. (B) A taste receptor cell responded to a 20-s application of 10 mM denatonium benzoate (hatched column) with a small slow calcium increase.