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OS increases bone mass in intact mice. (A) Femoral metaphyses from mice with median BV/TV. (B) Trabecular bone volume density (BV/TV). (C) Trabecular number (Tb.N). (D) Trabecular thickness (Tb.Th). (E) Connectivity density (Conn.D). (F) Serum osteoclacin. (G) Serum TRAP5b. OS, synthetic N-oleoyl l-serine. Data are mean ± SE obtained in 8–12 mice per condition. *Versus VEH; P < 0.05.
