Table 2. Activation of signal pathways in TAC and Shunt.

Activation of signal pathways in TAC and Shunt 24 hours and 7 days after intervention. Changes are expressed relative to the corresponding Sham (n=6 per group);

	24h		7d
	TAC	Shunt	TAC	Shunt
P-CaMKII/GAPDH	77.5±28.1%*	-8.9±18.6%	81.5±32.6%*	-20.0±16.7%
CaMKII/GAPDH	23.7±9.1%	-10.0±14.3%	23.7±9.1%*	-10.0±14.3%
P-CaMKII/CaMKII	66.3±22.9%+	3.3±22.3%	28.6±22.9%	-9.2±16.4%
P-Akt/Akt	9.3±18.5%	70.2±30.4%*	22.3±18.5%	41.3±17.8%*
P-p38/GAPDH	8.1±20.4%	44.7±18.4%*	15.8±19.9%	-20.6±14.0%
p38/GAPDH	-26.0±12.4%	-23.1±9.6%*	-35.1±8.9%*	-29.4±12.4%*
P-p38/p38	47.8±19.7%*	124.5±36.7%+	92.9±30.0%*	0.6±13.7%
P-ERK/ERK	74.3±29.2%*	4.2±19.5%	-61.4±23.6%*	17.5±35.4%
P-JNK/JNK	0.1±25.4%	0.1±15.1%	-50.7±36.0%	82.3±38.5%
P-HDAC/CS			107.4±37.8%*	7.7±17.4%
P-GSK3ß/GSK3ß	4.0±9.5%	26.3±11.3%*	-7.1±11.9%	-8.3±16.2%
MCIP/GAPDH	-7.6±2.1%	3.1±4.0%	454.7±105.3%*	55.3±46.7%

^*P<0.05;

⁺P<0.01

Normalization is done per GAPDH or per calsequestrin (CS) or per respective protein