Figure 4. Crystal Structure of the ClpP-ADEP1 Complex.

(A) Ribbon diagram of the ClpP monomer with the N-terminal lid shown in purple and the head domain and handle shown in light blue. The secondary structure motifs are labeled as in (Wang et al., 1997).

(B) Orthogonal views of the ClpP tetradecamer (white surface) bound to ADEP1 (yellow color-coded sticks). The surfaces of two adjacent ClpP monomers are colored light green and blue for reference, and all the N-terminal loops are shown as a purple surface. Two 2-methyl-2,4-pentanediol (MPD) molecules bound to the P1 pocket and the side pores of each ClpP monomer are shown as brown sticks. See also Figure S4, S5, S6 and Movie S1.