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. Author manuscript; available in PMC: 2010 Oct 15.
Published in final edited form as: Genet Epidemiol. 2008 Apr;32(3):255–263. doi: 10.1002/gepi.20300

Figure 1.

Figure 1

Type 1 error for identifying an interaction when there is in fact no interaction effect, but there is a dominant main effect for two SNPs each with minor allele frequency 0.173 for various levels of two-stage testing (α1 < 1) and one-stage testing (α1 = 1).