. Author manuscript; available in PMC: 2010 Oct 15.

Published in final edited form as: Curr Opin Nephrol Hypertens. 1997 May;6(3):292–298. doi: 10.1097/00041552-199705000-00015

Table 1.

Differences between conventional bone marrow and organ transplantation

	Bone Marrow	Organ
Recipient cytoablation^*	Yes	No
MHC compatibility	Critical	Not critical
Principal complication	GVHD	Rejection
Drug free state	Common	Rare
Term for success	Tolerance	‘Acceptance’^**

AII differences derive from this therapeutic step, which in effect establishes an unopposed graft-versus-host (GVH) reaction in the bone marrow recipient whose countervailing immune reaction is eliminated.

^**

or ‘operational tolerance’. GVHD, graft-versus-host disease; MHC, major histocompatibility complex.