TABLE 3.
Effect in Dogs of Left Portal Branch Infusion for 4 Days of Acr-F4, Beginning 6 hr after Portacaval Shunt
| Labeled nuclei/1000 hepatocytes |
|||
|---|---|---|---|
| Substance | No. animals | Right lobe | Left lobe |
| Vehicle | 3 | 4.4 ± 0.6 | 4.8 ± 0.4 |
| Acr-F4 | 3 | 4.4 ± 0.5 | 12.2 ± 1.0† |
| Acr-F4 + Monoclonal Ab* | 4.1 ± 0.2 | 4.3 ± 0.3 | |
A mixture of active IgG(s), adding up to 150 µg of protein daily, was added to the vehicle containing Acr-F4 and incubated for 2 hr at 37 ° C before infusion.
Significantly different from control (P < 0.001 compared to all other groups).