Table 1. Result of the expression array: the top twenty induced (upper panel) and top twenty repressed (lower panel) genes.
TOP 20 induced genes | ||||
Entrez Gene Name | Entrez Gene ID | Arraya | q-value (%)b | qRTPCR RQ valuec |
LYZ | 4069 | 5,99 | 0,0000 | 5,41 |
FOSB | 2354 | 5,48 | 0,0000 | 5,62 |
IGJ | 3512 | 5,44 | 0,0000 | |
TRA@ | 6955 | 5,23 | 0,7897 | |
PAX8 | 7849 | 4,68 | 0,0000 | 2,55 |
CYBB | 1536 | 4,62 | 0,0000 | |
TRA@ | 6955 | 4,60 | 0,0000 | |
HLA-DQA1 | 3117 | 4,56 | 0,0000 | |
CECR1 | 51816 | 4,49 | 0,0000 | |
HLA-DQB1 | 3119 | 4,41 | 0,0000 | |
EGR1 | 1958 | 4,29 | 0,0000 | |
RNASE6 | 6039 | 3,98 | 0,0000 | |
SFRP2 | 6423 | 3,91 | 0,0000 | 4,74 |
GPNMB | 10457 | 3,87 | 0,0000 | 4,97 |
PABPC1 | 26986 | 3,85 | 0,0000 | |
MS4A6A | 64231 | 3,84 | 0,0000 | |
KLF4 | 9314 | 3,74 | 0,7897 | |
HADHA | 3030 | 3,61 | 0,7897 | |
FOS | 2353 | 3,61 | 0,0000 | 4,46 |
IGHG4 | 3503 | 3,52 | 0,7897 |
Array mean ratio are expressed in log2.
Q-values (i.e. minimal false discovery rate) are expressed in percent, all P-values are less than 0.001.
Validation with qRTPCR: RQ values are expressed in log2.
Bold characters indicate genes that are validated (13 of 14 tested) among these 40 genes.