Table 8.
Regulation of stress relevant gene sets comparing pre and post intervention gene expression within each group (FDR ≤ 5%)
| GSEA Gene Set Collections |
Number of up regulated Gene Sets | |||||
|---|---|---|---|---|---|---|
| Control Group |
Kiwifruit Group |
Antioxidant-Rich Diet Group |
||||
| Pre | Post | Pre | Post | Pre | Post | |
| DNA and repair (61) | 2 | 0 | 0 | 10 | 0 | 20 |
| Hypoxia* (33) | 0 | 0 | 0 | 2 | 0 | 3 |
| Apoptosis (209) | 1 | 3 | 0 | 21 | 0 | 30 |
| Cytokine* (164) | 0 | 3 | 0 | 9 | 0 | 8 |
| Interleukin* (98) | 1 | 1 | 0 | 10 | 0 | 2 |
| Immune* and response (62) | 0 | 2 | 0 | 11 | 0 | 6 |
| Inflammation (7) | 0 | 0 | 0 | 2 | 0 | 0 |
| Stress and response (51) | 0 | 1 | 0 | 0 | 0 | 8 |
| Stress (91) | 0 | 0 | 0 | 0 | 0 | 11 |
| Oxidative and stress (32) | 0 | 0 | 0 | 0 | 0 | 1 |
| C3TFT (582) | 0 | 0 | 1 | 0 | 0 | 45 |
1Collections of gene sets were obtained using a gene set browser from the Broad Institute website http://www.broad.mit.edu/gsea/ defined by the listed keywords. For some keywords we used truncated search terms as indicated by *.
2Number of gene sets in each collection passing the gene set size filter is given in parentheses.
3The C3 TFT gene set collection consists of gene sets grouped by common transcription factor binding sites.