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Tolbutamide response in SUR1-R1530C. Whole-cell currents recorded from Xenopus oocytes coexpressing Kir6.2 and either SUR1 (WT) or SUR1-R1530C in response to voltage steps of +20 mV from a holding potential of -10 mV. Bars indicate the times of application of 3 mmol/l azide or 0.5 mmol/l tolbutamide.
