Table 5.

Comparison of prediction performance by net reclassification improvement (NRI) and integrated difference improvement (IDI) with relative 95% confidence interval (CI) and significance levels

Comparison set	Models	NRI*	95% CI	P value	IDI	95% CI	P value
1	Clinical coefficient-based vs. Cambridge	0.066	-0.054 - 0.186	0.28	0.007	-0.001 - 0.014	0.051
2	Biochemical coefficient-based vs. Cambridge	0.294	0.141 - 0.447	0.0004	0.021	0.004 - 0.037	0.008
3	Biochemical coefficient-based vs. clinical coefficient-based	0.244	0.122 - 0.366	0.0002	0.014	-0.002 - 0.030	0.053
4	Clinical coefficient-based vs. clinical point-based	0.090	-0.022 - 0.203	0.23	0.009	-0.001 - 0.019	0.057
5	Biochemical coefficient-based vs. biochemical point-based	0.362	0.262 - 0.462	0.0003	0.023	0.005 - 0.041	0.006
6	Biochemical point-based vs. clinical point-based	-0.015	-0.139 - 0.109	0.82	0.00003	-0.001 - 0.001	0.49

*Presumed risk categories for NRI according to quartile values (0.6%, 1.2% and 2.6%)