. 2010 Sep 25;17(1):78. doi: 10.1186/1423-0127-17-78

Table 1.

Serotonin and metabolites in the hippocampus of control and experimental rats

Experimental Groups	5-HT (nmoles/g wet wt. of tissue)	5HIAA (nmoles/g wet wt. of tissue)	5-HIAA/ 5-HT
Control	1.56 ± 0.27	1.94 ± 0.22	1.24 ± 0.23
Diabetic	0.89 ± 0.29 ^a	2.93 ± 0.31 ^a	3.29 ± 0.28 ^a
Diabetic+Insulin	1.07 ± 0.19 ^{a, b}	2.29 ± 0.20 ^{a, b}	2.14 ± 0.20 ^a
Diabetic+Pyridoxine	0.98 ± 0.33 ^{a, b}	2.91 ± 0.36 ^a	2.96 ± 0.33 ^a
Diabetic+Insulin+Pyridoxine	1.45 ± 0.35 ^c	1.53 ± 0.29 ^c	1.05 ± 0.31 ^c
Diabetic+A. marmelose	1.10 ± 0.23 ^{a, b}	2.73 ± 0.24 ^{a, b}	2.48 ± 0.21 ^a
*Diabetic+A. marmelose+Pyridoxine*	1.59 ± 0.22 ^c	1.66 ± 0.22 ^c	1.04 ± 0.21 ^c

Values are mean ± S.E.M of 4-6 separate experiments. Each group consists of 6-8 rats.

^ap < 0.001 when compared to control;

^bp < 0.01, ^cp < 0.001 when compared to diabetic group.