Table 2.

[³H] 5-Hydroxytryptamine binding parameters in the hippocampus of control and experimental rats

Experimental Groups	Bmax (fmoles/mg protein)	Kd (nM)
Control	212.5 ± 2.11	3.22 ± 0.54
Diabetic	72.4 ± 3.21 a	1.94 ± 0.41 a
Diabetic + Insulin	62.8 ± 2.06 a	1.40 ± 0.29 a
Diabetic + Pyridoxine	148.4 ± 2.33 a, c	2.60 ± 0.49 b
Diabetic + Insulin+ Pyridoxine	196.0 ± 1.43 c	3.20 ± 0.17 c
Diabetic+A. marmelose	140.1 ± 4.33 a, c	2.57 ± 1.42 b
Diabetic+ A. marmelose +Pyridoxine	186.4 ± 2.42 c	3.05 ± 1.31 c

Values are mean ± S.E.M of 6-8 separate experiments. Each group consists of 6-8 rats.

^a p < 0.001, ^b p < 0.05 when compared to control group; ^c p < 0.001 when compared to diabetic group.