Table 1. X+XO treatment has no adverse effect on body weight, food or water intake and body temperature.

Fifty grams of rodent chow (diet pellets) and 50 ml of tap water per rat was provided to the rats every day. The amount of food and water consumed was measured by weighing the left-over diet pellets and drinking water 24 hours later. Data collected were averaged for each treatment group of rats on the last day of the experiment before behavior testing. Rectal temperature was manually recorded using animal rectal probe every day after 30 min of X+XO-treatment/vehicle injections. N=8-12 rats

General Parameters	CONTROL	X+XO
Body Weight (g)	225 ± 1.0	223 ± 2.1
Food Intake (g)	22.4 ± 4.0	21.6 ± 3.8
Water Intake (ml)	24 ± 2.1	23 ± 2.0
Body Temperature (°C)	37.84 ± 0.22	36.6 ± 0.32