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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Biol Psychiatry. 2010 Aug 17;68(9):801–810. doi: 10.1016/j.biopsych.2010.06.019

Figure 2. Effect of Cacna1c HET knockout on risk-taking and anxiety-like behavior.

Figure 2

(a) Male HET mice had no significant difference in center time in a large open field. (b) Female HET mice spent less time in the center of a large open field. (c) There was no significant difference in time spent on the open arms of the elevated plus maze in male HET mice. (d) Female HET mice spent less time on the open arms of the elevated plus maze. (e) There was no significant difference in the time male HET mice spent in the light compartment of the light-dark box. (f) Female HET mice spent less time in the light compartment of the light-dark box. There was no significant effect of genotype in either (g) male or (h) female to modify latency to drink in the novel cage when compared to WT mice. There was no significant effect of genotype in either (i) male or (j) female subjects to modify hyperthermia in response to stress. Data are expressed as mean ± SEM. *, P≤0.05; ***, P<0.001.