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. Author manuscript; available in PMC: 2010 Oct 16.
Published in final edited form as: Gastroenterology. 2008 Apr 22;135(2):591–600. doi: 10.1053/j.gastro.2008.04.019

Figure 1. Restricted Foxq1 expression in fetal and adult stomach.

Figure 1

(A) RT-PCR results from the GIFT database 9. RNA from wild-type murine stomach (St) and intestine (In) at four different fetal stages (E11, E13, E15, E17) probed using Foxq1-specific primers. Foxq1 is expressed in the stomach with increasing abundance as the embryo approaches birth, but not detected in intestine. (B) RT-PCR in adult mouse stomach shows robust Foxq1 mRNA levels relative to the intestine; GAPDH was used as a loading control. (D–F) In situ hybridization on adult wild-type murine stomach using Foxq1 antisense probe (D), sense control (E) or Muc5AC antisense probe (F). The Foxq1 probe gave strong signal in surface epithelium (arrows) throughout the glandular stomach (images shown here are taken from the corpus, with an H&E-stained section as a reference (C)) and considerably weaker signal in chief cells (arrowheads); Muc5ac is specific to surface mucous cells (arrows in F). p, Parietal cells.