. Author manuscript; available in PMC: 2010 Oct 16.

Published in final edited form as: Food Chem Toxicol. 2007 Jun 15;45(12):2359–2365. doi: 10.1016/j.fct.2007.06.012

Table 1.

Inhibition of human P450_2E1 by various extracts (the total volume for each reaction was 0.500 mL).

Extract	[p-nitrophenol]	Enzyme	% inhibition
Echinacea extracted in 95% ethanol (2 µL)	0.020 mM	HLM	27 %
Echinacea extracted in 95% ethanol (2 µL)	0.020 mM	Expressed 2E1	29 %
Echinacea extract in 33 % ethanol (2µL)	0.020 mM	HLM	0 %
Echinacea extract in 33 % ethanol (2µL)	0.020 mM	Expressed 2E1	0 %
Spilanthes extracted in 95 % ethanol (40 µL)	0.020 mM	HLM	40 %
Spilanthes extracted in 95 % ethanol (40 µL)	0.020 mM	Expressed 2E1	60 %